产品名称
B3GN2 Rabbit Polyclonal Antibody
基因名称
B3GNT2 B3GALT7 B3GNT1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/10678
Human Swissprot No.
Q9NY97
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NY97/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/53625
Mouse Swissprot No.
Q9Z222
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Z222
免疫原
Synthesized peptide derived from human B3GN2 AA range: 190-240
特异性
This antibody detects endogenous levels of B3GN2 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein. It prefers the substrate of lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jan 2016],
细胞定位
Golgi apparatus membrane ; Single-pass type II membrane protein .
功能
catalytic activity:UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl-R.,caution:Was indicated as B3Gal-T6 in submitted DNA entries.,cofactor:Manganese.,function:Can initiate the synthesis or the elongation of the linear poly-N-acetyllactosaminoglycans.,function:Catalyzes the initiation and elongation of poly-N-acetyllactosamine chains.,online information:GlycoGene database,online information:N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase,online information:UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1,pathway:Protein modification; protein glycosylation.,similarity:Belongs to the glycosyltransferase 31 family.,tissue specificity:In the adult, highly expressed in heart, brain, skeletal muscle and kidney and to a lesser extent in placenta, pancreas, spleen, prostate, testis, ovary, small intestine and colon. Very weak expression in lung, liver, thymus and peripheral blood leukocytes. In fetal highly expressed in brain and kidney and to a lesser extent in lung and liver.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
