BD-PP0325

CD32 (phospho Tyr292) Rabbit Polyclonal Antibody

FCGR2B; CD32; FCG2; IGFR2; Low affinity immunoglobulin gamma Fc region receptor II-b; IgG Fc receptor II-b; CDw32; Fc-gamma RII-b; Fc-gamma-RIIb; FcRII-b; CD antigen CD32

常规抗体

FCGR2B

Low affinity immunoglobulin gamma Fc region receptor II-b

WB

Human,Mouse,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

2213

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2213

P31994

http://www.uniprot.org/uniprotkb/P31994/entry

The antiserum was produced against synthesized peptide derived from human CD32 around the phosphorylation site of Tyr292. AA range:258-307

Phospho-CD32 (Y292) Polyclonal Antibody detects endogenous levels of CD32 protein only when phosphorylated at Y292.

WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

32kD

-20°C/1 year

Polyclonal, Rabbit,IgG

The Fc fragment of IgG receptor IIb encoded by FCGR2B is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.

Is the most broadly distributed Fc-gamma-receptor. Expressed in monocyte, neutrophils, macrophages, basophils, eosinophils, Langerhans cells, B-cells, platelets cells and placenta (endothelial cells). Not detected in natural killer cells.

Cell membrane; Single-pass type I membrane protein.

B_Cell_Antigen;Fc gamma R-mediated phagocytosis;Systemic lupus erythematosus;

immune response,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.