产品名称
T132E Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/124842
Human Swissprot No.
Q6IEE7
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q6IEE7/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/270893
Mouse Swissprot No.
Q6IEE6
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q6IEE6
免疫原
Synthesized peptide derived from human T132E AA range: 486-536
特异性
This antibody detects endogenous levels of T132E at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
细胞定位
Membrane ; Single-pass type I membrane protein .
功能
disease:TMEM132E gene is identified as one gene located in a region involved in a heterozygous deletion of approximately 4.7 Mb; this deletion, involving the NF1 gene and contiguous genes lying in its flanking regions, is observed in one patient with NF1 and 17q11.2 microdeletion syndrome [MIM:162200]. The NF1 microdeletion syndrome is often characterized by a more severe phenotype than that observed in the majority of NF1 patients. Indeed, patients with NF1 microdeletion often show variable facial dysmorphism, mental retardation, developmental delay, and an excessive number of neurofibromas.,similarity:Belongs to the TMEM132 family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
