产品名称
Pragmin (phospho Tyr413) Rabbit Polyclonal Antibody
别名
SGK223; Tyrosine-protein kinase SgK223; Sugen kinase 223
蛋白名称
Tyrosine-protein kinase SgK223
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=157285
Human Swissprot No.
Q86YV5
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q86YV5/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=244418
Mouse Swissprot No.
Q571I4
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q571I4
免疫原
Synthesized phospho-peptide around the phosphorylation site of human Pragmin (phospho Tyr413)
特异性
Phospho-Pragmin (Y413) Polyclonal Antibody detects endogenous levels of Pragmin protein only when phosphorylated at Y413.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes an enzyme that belongs to the tyrosine protein kinase family. A similar protein in rat binds to Rho family GTPase 2 (Rnd2) and regulates neurite outgrowth via activation of Ras homolog gene family, member A (RhoA). [provided by RefSeq, Mar 2014],
组织表达
Amygdala,Epithelium,Fetal brain,Spleen,
细胞定位
Cytoplasm . Cell junction, focal adhesion . Nucleus . Colocalized with NOTCH1 in the nucleus. .
功能
catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,similarity:Belongs to the protein kinase superfamily.,similarity:Contains 1 protein kinase domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
