产品名称
ABTB1 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/80325
Human Swissprot No.
Q969K4
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q969K4/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/80283
Mouse Swissprot No.
Q99LJ2
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q99LJ2
Rat Gene Link
https://www.uniprot.org/uniprot/297432
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5XIU1
免疫原
Synthesized peptide derived from human ABTB1 AA range: 163-213
特异性
This antibody detects endogenous levels of ABTB1 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein with an ankyrin repeat region and two BTB/POZ domains, which are thought to be involved in protein-protein interactions. Expression of this gene is activated by the phosphatase and tensin homolog, a tumor suppressor. Alternate splicing results in three transcript variants. [provided by RefSeq, Mar 2010],
组织表达
Ubiquitously expressed in all fetal tissues examined including heart, brain, liver, and kidney. Also expressed at lower levels in both adult heart and hypertrophic heart.
功能
function:May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes.,similarity:Contains 2 ANK repeats.,similarity:Contains 2 BTB (POZ) domains.,tissue specificity:Ubiquitously expressed in all fetal tissues examined including heart, brain, liver, and kidney. Also expressed at lower levels in both adult heart and hypertrophic heart.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
