产品名称
Pragmin (phospho Tyr413) Rabbit Polyclonal Antibody
别名
SGK223; Tyrosine-protein kinase SgK223; Sugen kinase 223
蛋白名称
Tyrosine-protein kinase SgK223
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=157285
Human Swissprot No.
Q86YV5
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q86YV5/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=244418
Mouse Swissprot No.
Q571I4
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q571I4
免疫原
Synthesized phospho-peptide around the phosphorylation site of human Pragmin (phospho Tyr413)
特异性
Phospho-Pragmin (Y413) Polyclonal Antibody detects endogenous levels of Pragmin protein only when phosphorylated at Y413.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes an enzyme that belongs to the tyrosine protein kinase family. A similar protein in rat binds to Rho family GTPase 2 (Rnd2) and regulates neurite outgrowth via activation of Ras homolog gene family, member A (RhoA). [provided by RefSeq, Mar 2014],
组织表达
Amygdala,Epithelium,Fetal brain,Spleen,
细胞定位
Cytoplasm . Cell junction, focal adhesion . Nucleus . Colocalized with NOTCH1 in the nucleus. .
功能
catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,similarity:Belongs to the protein kinase superfamily.,similarity:Contains 1 protein kinase domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
