产品名称
SPY1 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/10252
Human Swissprot No.
O43609
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O43609/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/24063
Mouse Swissprot No.
Q9QXV9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9QXV9
免疫原
Synthesized peptide derived from human SPY1 AA range: 129-179
特异性
This antibody detects endogenous levels of SPY1 at Human/Mouse
稀释度
WB 1：500-2000,IP 1：50-100
宿主
Polyclonal, Rabbit,IgG
细胞定位
Cytoplasm. Membrane; Peripheral membrane protein. Found in the cytoplasm in unstimulated cells but is translocated to the membrane ruffles in cells stimulated with EGF (epidermal growth factor).
功能
domain:The Cys-rich domain is responsible for the localization of the protein to the membrane ruffles.,function:May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis.,induction:By FGF signaling.,similarity:Belongs to the sprouty family.,similarity:Contains 1 SPR (sprouty) domain.,subcellular location:Found in the cytoplasm in unstimulated cells but is translocated to the membrane ruffles in cells stimulated with EGF (epidermal growth factor).,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
