产品名称
DSCR3 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/10311
Human Swissprot No.
O14972
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O14972/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/13185
Mouse Swissprot No.
O35075
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/O35075
免疫原
Synthesized peptide derived from human DSCR3 AA range: 163-213
特异性
This antibody detects endogenous levels of DSCR3 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined. [provided by RefSeq, Jul 2008],
组织表达
Ubiquitously expressed.
功能
similarity:Belongs to the VPS26 family.,tissue specificity:Ubiquitously expressed.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
