产品名称
COPT1 Rabbit Polyclonal Antibody
蛋白名称
High affinity copper uptake protein 1 (Copper transporter 1) (hCTR1) (Solute carrier family 31 member 1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
O15431
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O15431/entry
Mouse Swissprot No.
Q8K211
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8K211
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q9JK41
免疫原
Synthesized peptide derived from part region of human protein
特异性
COPT1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a high-affinity copper transporter found in the cell membrane. The encoded protein functions as a homotrimer to effect the uptake of dietary copper. [provided by RefSeq, Aug 2011],
组织表达
Brain,Liver,Lung,Skeletal muscle,Skin,
细胞定位
Cell membrane; Multi-pass membrane protein. Localizes to the apical membrane in intestinal epithelial cells. .
功能
function:Involved in high-affinity copper uptake.,PTM:O-Glycosylation at Thr-27 protects from proteolytic cleavage in the N-terminal extracellular domain.,similarity:Belongs to the SLC31A transporter family.,subunit:Homotrimer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
