产品名称
DB118 Rabbit Polyclonal Antibody
基因名称
DEFB118 C20orf63 DEFB18 ESC42
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/117285
Human Swissprot No.
Q96PH6
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q96PH6/entry
免疫原
Synthesized peptide derived from human DB118 AA range: 38-88
特异性
This antibody detects endogenous levels of DB118 at Human
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the beta subfamily of defensins. Beta-defensins are antimicrobial peptides that protect tissues and organs from infection by a variety of microorganisms. Expression of this gene is regulated by androgen, and the encoded protein binds to sperm and exhibits antibacterial activity against E. coli. This gene is found in a cluster with other beta-defensin genes on the long arm of chromosome 20. [provided by RefSeq, Nov 2014],
组织表达
High-level and epididymis-specific expression (PubMed:12600824). Most abundant in the epithelium of the caput and present in the epididymis lumen and bound to sperm (PubMed:12600824). Also expressed in pancreas (PubMed:12600824).
功能
function:Has antibacterial activity .,similarity:Belongs to the beta-defensin family.,tissue specificity:High-level and epididymis-specific expression. Most abundant in the epithelium of the caput and is also present in the lumen and bound to sperm. Expressed also in pancreas.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
