产品名称
COPT1 Rabbit Polyclonal Antibody
蛋白名称
High affinity copper uptake protein 1 (Copper transporter 1) (hCTR1) (Solute carrier family 31 member 1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
O15431
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O15431/entry
Mouse Swissprot No.
Q8K211
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8K211
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q9JK41
免疫原
Synthesized peptide derived from part region of human protein
特异性
COPT1 Polyclonal Antibody detects endogenous levels of protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a high-affinity copper transporter found in the cell membrane. The encoded protein functions as a homotrimer to effect the uptake of dietary copper. [provided by RefSeq, Aug 2011],
组织表达
Brain,Liver,Lung,Skeletal muscle,Skin,
细胞定位
Cell membrane; Multi-pass membrane protein. Localizes to the apical membrane in intestinal epithelial cells. .
功能
function:Involved in high-affinity copper uptake.,PTM:O-Glycosylation at Thr-27 protects from proteolytic cleavage in the N-terminal extracellular domain.,similarity:Belongs to the SLC31A transporter family.,subunit:Homotrimer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
