产品名称
RBMS1 Rabbit Polyclonal Antibody
基因名称
RBMS1 C2orf12 MSSP MSSP1 SCR2
蛋白名称
RNA-binding motif, single-stranded-interacting protein 1 (Single-stranded DNA-binding protein MSSP-1) (Suppressor of CDC2 with RNA-binding motif 2)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P29558
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P29558/entry
Mouse Swissprot No.
Q91W59
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q91W59
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q5PQP1
免疫原
Synthesized peptide derived from part region of human protein
特异性
RBMS1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. Several transcript variants, resulting from alternative splicing and encoding different isoforms, have been described. A pseudogene for this locus is found on chromosome 12. [provided by RefSeq, Feb 2009],
组织表达
Highest amounts are found in placenta, lung and heart.
功能
developmental stage:Expressed at highest levels during the G1 to S transition of the cell cycle.,function:Single-stranded DNA binding protein that interacts with the region upstream of the C-myc gene. Binds specifically to the DNA sequence motif 5'-[AT]CT[AT][AT]T-3'. Probably has a role in DNA replication.,sequence caution:Translation N-terminally extended.,similarity:Contains 2 RRM (RNA recognition motif) domains.,tissue specificity:Highest amounts are found in placenta, lung and heart.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
