产品名称
RAB14 Rabbit Polyclonal Antibody
蛋白名称
Ras-related protein Rab-14
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P61106
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P61106/entry
Mouse Swissprot No.
Q91V41
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q91V41
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P61107
免疫原
Synthesized peptide derived from part region of human protein
特异性
RAB14 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
RAB14 belongs to the large RAB family of low molecular mass GTPases that are involved in intracellular membrane trafficking. These proteins act as molecular switches that flip between an inactive GDP-bound state and an active GTP-bound state in which they recruit downstream effector proteins onto membranes (Junutula et al., 2004 [PubMed 15004230]).[supplied by OMIM, Mar 2009],
组织表达
Adrenal gland,B-cell lymphoma,Brain,Liver,Melanoma,Placenta,Platele
细胞定位
Recycling endosome . Early endosome membrane ; Lipid-anchor ; Cytoplasmic side . Golgi apparatus membrane ; Lipid-anchor ; Cytoplasmic side . Golgi apparatus, trans-Golgi network membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasmic vesicle, phagosome . Recruited to recycling endosomes by DENND6A (PubMed:22595670). Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211). .
功能
function:May be involved in vesicular trafficking and neurotransmitter release.,similarity:Belongs to the small GTPase superfamily. Rab family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
