产品名称
STAR3 Rabbit Polyclonal Antibody
蛋白名称
StAR-related lipid transfer protein 3 (Metastatic lymph node gene 64 protein) (MLN 64) (Protein CAB1) (START domain-containing protein 3) (StARD3)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q14849
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q14849/entry
Mouse Swissprot No.
Q61542
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q61542
免疫原
Synthesized peptide derived from part region of human protein
特异性
STAR3 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
StAR related lipid transfer domain containing 3(STARD3) Homo sapiens This gene encodes a member of a subfamily of lipid trafficking proteins that are characterized by a C-terminal steroidogenic acute regulatory domain and an N-terminal metastatic lymph node 64 domain. The encoded protein localizes to the membranes of late endosomes and may be involved in exporting cholesterol. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009],
组织表达
Expressed in retina.
细胞定位
Late endosome membrane ; Multi-pass membrane protein . Localizes to contact sites between the endoplasmic reticulum and late endosomes: associates with the endoplasmic reticulum membrane via interaction with VAPA, VAPB or MOSPD2. .
功能
function:Binds and transports cholesterol. Promotes steroidogenesis in placenta and brain.,similarity:Contains 1 MENTAL domain.,similarity:Contains 1 START domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.