产品名称
ATOH7 Rabbit Polyclonal Antibody
蛋白名称
Protein atonal homolog 7 (Class A basic helix-loop-helix protein 13) (bHLHa13) (Helix-loop-helix protein hATH-5) (hATH5)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q8N100
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8N100/entry
Mouse Swissprot No.
Q9Z2E5
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9Z2E5
免疫原
Synthesized peptide derived from part region of human protein
特异性
ATOH7 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This intronless gene encodes a member of the basic helix-loop-helix family of transcription factors, with similarity to Drosophila atonal gene that controls photoreceptor development. Studies in mice suggest that this gene plays a central role in retinal ganglion cell and optic nerve formation. Mutations in this gene are associated with nonsyndromic congenital retinal nonattachment. [provided by RefSeq, Dec 2011],
细胞定位
Nucleus . Perikaryon . Cell projection, axon .
功能
function:Transcription factor involved in the differentiation of retinal ganglion cells.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.