产品名称
STAR3 Rabbit Polyclonal Antibody
蛋白名称
StAR-related lipid transfer protein 3 (Metastatic lymph node gene 64 protein) (MLN 64) (Protein CAB1) (START domain-containing protein 3) (StARD3)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q14849
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q14849/entry
Mouse Swissprot No.
Q61542
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q61542
免疫原
Synthesized peptide derived from part region of human protein
特异性
STAR3 Polyclonal Antibody detects endogenous levels of protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
StAR related lipid transfer domain containing 3(STARD3) Homo sapiens This gene encodes a member of a subfamily of lipid trafficking proteins that are characterized by a C-terminal steroidogenic acute regulatory domain and an N-terminal metastatic lymph node 64 domain. The encoded protein localizes to the membranes of late endosomes and may be involved in exporting cholesterol. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009],
组织表达
Expressed in retina.
细胞定位
Late endosome membrane ; Multi-pass membrane protein . Localizes to contact sites between the endoplasmic reticulum and late endosomes: associates with the endoplasmic reticulum membrane via interaction with VAPA, VAPB or MOSPD2. .
功能
function:Binds and transports cholesterol. Promotes steroidogenesis in placenta and brain.,similarity:Contains 1 MENTAL domain.,similarity:Contains 1 START domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.