产品名称
TXD11 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/51061
Human Swissprot No.
Q6PKC3
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q6PKC3/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/106200
Mouse Swissprot No.
Q8K2W3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8K2W3
免疫原
Synthesized peptide derived from human TXD11 AA range: 110-160
特异性
This antibody detects endogenous levels of TXD11 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
组织表达
Widely expressed at low level. Expressed at higher level in thyroid and prostate.
细胞定位
Endoplasmic reticulum membrane ; Single-pass membrane protein .
功能
function:May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation.,sequence caution:Intron retention.,similarity:Belongs to the protein disulfide isomerase family.,similarity:Contains 2 thioredoxin domains.,subunit:Interacts with the cytoplasmic part of DUOX1 and DUOX2. Interacts with TPO and CYBA.,tissue specificity:Widely expressed at low level. Expressed at higher level in thyroid and prostate.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
