BD-PN2951

MARE3 Rabbit Polyclonal Antibody

常规抗体

MAPRE3

Microtubule-associated protein RP/EB family member 3 (EB1 protein family member 3) (EBF3) (End-binding protein 3) (EB3) (RP3)

WB

Human,Mouse,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.

22924

Q9UPY8

https://www.uniprot.org/uniprotkb/Q9UPY8/entry

Q6PER3

http://www.uniprot.org/uniprot/Q6PER3

Q5XIT1

http://www.uniprot.org/uniprot/O54941Q5XIT1

Synthesized peptide derived from part region of human protein

MARE3 Polyclonal Antibody detects endogenous levels of protein.

WB 1:500-2000 ELISA 1:5000-20000

30kD

-20°C/1 year

Polyclonal, Rabbit,IgG

The protein encoded by this gene is a member of the RP/EB family of genes. The protein localizes to the cytoplasmic microtubule network and binds APCL, a homolog of the adenomatous polyposis coli tumor suppressor gene. [provided by RefSeq, Jul 2008],

Predominantly expressed in brain and muscle.

Cytoplasm, cytoskeleton . Associated with the microtubule network. Detected at the plus end of microtubules. .

domain:Composed of two functionally independent domains. The N-terminal domain forms an hydrophobic cleft involved in microtubule binding and the C-terminal is involved in the formation of mutually exclusive complexes with APC and DCTN1.,function:May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration.,similarity:Belongs to the MAPRE family.,similarity:Contains 1 CH (calponin-homology) domain.,similarity:Contains 1 EB1 C-terminal domain.,subcellular location:Associated with the microtubule network.,subunit:Interacts with APC2 (By similarity). Interacts with DCTN1. Binds to the C-terminal domain of APC. Binds monomeric and polymerized tubulin.,tissue specificity:Predominantly expressed in brain and muscle.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.