产品名称
HHEX Rabbit Polyclonal Antibody
蛋白名称
Hematopoietically-expressed homeobox protein HHEX (Homeobox protein HEX) (Homeobox protein PRH)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q03014
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q03014/entry
Mouse Swissprot No.
P43120
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P43120
免疫原
Synthesized peptide derived from part region of human protein
特异性
HHEX Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the homeobox family of transcription factors, many of which are involved in developmental processes. Expression in specific hematopoietic lineages suggests that this protein may play a role in hematopoietic differentiation. [provided by RefSeq, Jul 2008],
组织表达
Liver and promyelocytic leukemia cell line HL-60.
信号通路
Maturity onset diabetes of the young;
功能
developmental stage:Expressed during hematopoiesis.,function:Recognizes the DNA sequence 5'-ATTAA-3'. Transcriptional repressor. May play a role in hematopoietic differentiation. Establishes anterior identity at two levels; acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL.,similarity:Contains 1 homeobox DNA-binding domain.,tissue specificity:Liver and promyelocytic leukemia cell line HL60.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
