产品名称
LSHB Rabbit Polyclonal Antibody
蛋白名称
Lutropin subunit beta (Lutropin beta chain) (Luteinizing hormone subunit beta) (LH-B) (LSH-B) (LSH-beta)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P01229
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P01229/entry
Mouse Swissprot No.
O09108
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O09108
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P01230
免疫原
Synthesized peptide derived from part region of human protein
特异性
LSHB Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism. [provided by RefSeq, Jul 2008],
信号通路
Neuroactive ligand-receptor interaction;GnRH;
功能
disease:Defects in LHB are a cause of hypogonadism [MIM:152780]. Hypogonadism is characterized by infertility and pseudohermaphroditism.,function:Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.,online information:Luteinizing hormone entry,online information:The Singapore human mutation and polymorphism database,similarity:Belongs to the glycoprotein hormones subunit beta family.,subunit:Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin.,tissue specificity:Pituitary gland.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
