产品名称
TGM3 Rabbit Polyclonal Antibody
蛋白名称
Protein-glutamine gamma-glutamyltransferase E (EC 2.3.2.13) (Transglutaminase E) (TG(E)) (TGE) (TGase E) (Transglutaminase-3) (TGase-3) [Cleaved into: Protein-glutamine gamma-glutamyltransferase E 50 kDa catalytic chain; Protein-glutamine gamma-glutamyltransferase E 27 kDa non-catalytic chain]
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q08188
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q08188/entry
Mouse Swissprot No.
Q08189
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q08189
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941D4A5U3
免疫原
Synthesized peptide derived from part region of human protein
特异性
TGM3 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene consists of two polypeptide chains activated from a single precursor protein by proteolysis. The encoded protein is involved the later stages of cell envelope formation in the epidermis and hair follicle. [provided by RefSeq, Jul 2008],
组织表达
Foreskin,Osteosarcoma,Tongue,
功能
catalytic activity:Protein glutamine + alkylamine = protein N(5)-alkylglutamine + NH(3).,cofactor:Binds 1 calcium ion per subunit.,function:Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. It is responsible for the later stages of cell envelope formation in the epidermis and the hair follicle.,PTM:Activated by proteolytic processing.,similarity:Belongs to the transglutaminase superfamily. Transglutaminase family.,subunit:This enzyme consists of two polypeptide chains, which are synthesized as a precursor form of a single polypeptide.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
