产品名称
SIA8B Rabbit Polyclonal Antibody
蛋白名称
Alpha-2,8-sialyltransferase 8B (EC 2.4.99.-) (Sialyltransferase 8B) (SIAT8-B) (Sialyltransferase X) (STX) (Sialytransferase St8Sia II) (ST8SiaII)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q92186
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q92186/entry
Mouse Swissprot No.
O35696
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O35696
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q07977
免疫原
Synthesized peptide derived from part region of human protein
特异性
SIA8B Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a type II membrane protein that is thought to catalyze the transfer of sialic acid from CMP-sialic acid to N-linked oligosaccharides and glycoproteins. The encoded protein may be found in the Golgi apparatus and may be involved in the production of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). This protein is a member of glycosyltransferase family 29. [provided by RefSeq, Jul 2008],
组织表达
Highly expressed in fetal brain, kidney and heart and to a much lesser extent in adult heart and thymus.
细胞定位
Golgi apparatus membrane ; Single-pass type II membrane protein .
功能
function:May transfer sialic acid through alpha-2,8-linkages to the alpha-2,3-linked and alpha-2,6-linked sialic acid of N-linked oligosaccharides of glycoproteins and may be involved in PSA (polysialic acid) expression.,online information:GlycoGene database,online information:ST8Sia II,pathway:Protein modification; protein glycosylation.,similarity:Belongs to the glycosyltransferase 29 family.,tissue specificity:Highly expressed in fetal brain, kidney and heart and to a much lesser extent in adult heart and thymus.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
