产品名称
CDRT1 Rabbit Polyclonal Antibody
基因名称
CDRT1 C17orf1 C17orf1A HREP
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/374286
Human Swissprot No.
O95170
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O95170/entry
免疫原
Synthesized peptide derived from human CDRT1 AA range: 364-414
特异性
This antibody detects endogenous levels of CDRT1 at Human
宿主
Polyclonal, Rabbit,IgG
背景介绍
Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008],
组织表达
Expressed in pancreas, heart and skeletal muscle.
功能
miscellaneous:CDRT1 gene is located centromeric to and partially within proximal CMT1A-REP element. CMT1A-REP is a complex binary repeat element flanking a 1.5-Mb DNA region duplicated in Charcot-Marie-Tooth disease type I (CMT1A) or deleted in Hereditary neuropathy (HNPP).,similarity:Contains 4 WD repeats.,tissue specificity:Expressed in pancreas, heart and skeletal muscle.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
