产品名称
SRTD1 Rabbit Polyclonal Antibody
蛋白名称
SERTA domain-containing protein 1 (CDK4-binding protein p34SEI1) (SEI-1) (Transcriptional regulator interacting with the PHD-bromodomain 1) (TRIP-Br1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9UHV2
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9UHV2/entry
Mouse Swissprot No.
Q9JL10
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9JL10
免疫原
Synthesized peptide derived from part region of human protein
特异性
SRTD1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Acts at E2F-responsive promoters to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F-1/DP-1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of p16(INK4a).,similarity:Contains 1 SERTA domain.,subunit:Interacts with the PHD-bromodomain of TIF1, TRIM28/TIF1B and p300/CBP. Binds to DP1. Also interacts with CDK4.,
组织表达
Human small intestine,Mammary gland,Uterus,
功能
function:Acts at E2F-responsive promoters to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F-1/DP-1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of p16(INK4a).,similarity:Contains 1 SERTA domain.,subunit:Interacts with the PHD-bromodomain of TIF1, TRIM28/TIF1B and p300/CBP. Binds to DP1. Also interacts with CDK4.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
