产品名称
PCY1A Rabbit Polyclonal Antibody
蛋白名称
Choline-phosphate cytidylyltransferase A (EC 2.7.7.15) (CCT-alpha) (CTP:phosphocholine cytidylyltransferase A) (CCT A) (CT A) (Phosphorylcholine transferase A)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P49585
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P49585/entry
Mouse Swissprot No.
P49586
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P49586
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P19836
免疫原
Synthesized peptide derived from part region of human protein
特异性
PCY1A Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene belongs to the cytidylyltransferase family and is involved in the regulation of phosphatidylcholine biosynthesis. Mutations in this gene are associated with spondylometaphyseal dysplasia with cone-rod dystrophy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2015],
组织表达
Brain, placenta, liver, fetal and adult lung.
细胞定位
Cytoplasm, cytosol . Membrane ; Peripheral membrane protein . Endoplasmic reticulum . Nucleus . It can interconvert between an inactive cytosolic form and an active membrane-bound form. .
信号通路
Glycerophospholipid metabolism;
功能
catalytic activity:CTP + choline phosphate = diphosphate + CDP-choline.,enzyme regulation:By phosphorylation.,function:Controls phosphatidylcholine synthesis.,pathway:Phospholipid metabolism; phosphatidylcholine biosynthesis; phosphatidylcholine from phosphocholine: step 1/2.,PTM:The serine residues of the C-terminus are phosphorylated. The inactive soluble form is stabilized by phosphorylation, the active membrane bound form is promoted by anionic lipids or diacylglycerol, and is stabilized by dephosphorylation.,similarity:Belongs to the cytidylyltransferase family.,subcellular location:It can interconvert between an inactive cytosolic form and an active membrane-bound form.,subunit:Homodimer; disulfide-linked.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
