BD-PN2905

MGRN1 Rabbit Polyclonal Antibody

常规抗体

MGRN1 KIAA0544 RNF156

E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin RING finger protein 1) (RING finger protein 156)

WB

Human,Mouse,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.

23295

O60291

https://www.uniprot.org/uniprotkb/O60291/entry

Q9D074

http://www.uniprot.org/uniprot/Q9D074

Q5XIQ4

http://www.uniprot.org/uniprot/O54941Q5XIQ4

Synthesized peptide derived from part region of human protein

MGRN1 Polyclonal Antibody detects endogenous levels of protein.

WB 1:500-2000 ELISA 1:5000-20000

60kD

-20°C/1 year

Polyclonal, Rabbit,IgG

Mahogunin (MGRN1) is a C3HC4 RING-containing protein with E3 ubiquitin ligase activity in vitro.[supplied by OMIM, Apr 2004],

Brain,Leukocyte,

Early endosome . The endosomal localization is dependent on the interaction with TSG101.; [Isoform 1]: Cytoplasm, cytosol. Nucleus. Translocation from the cytosol to the nucleus is seen only in the presence of MC1R and MC4R, but not TBXA2R. Excluded from nucleoli.; [Isoform 2]: Cytoplasm, cytosol. Nucleus. Translocation from the cytosol to the nucleus is seen only in the presence of MC1R and MC4R, but not TBXA2R. Excluded from nucleoli.; [Isoform 3]: Cytoplasm, cytosol. Cell membrane.; [Isoform 4]: Cytoplasm, cytosol. Cell membrane.

Ubiquitin mediated proteolysis;

domain:The RING finger is required for ubiquitin ligase activity.,function:Probable E3 ubiquitin-protein ligase.,pathway:Protein modification; protein ubiquitination.,PTM:Autoubiquitinated in vitro.,similarity:Contains 1 RING-type zinc finger.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.