产品名称
SIA8B Rabbit Polyclonal Antibody
蛋白名称
Alpha-2,8-sialyltransferase 8B (EC 2.4.99.-) (Sialyltransferase 8B) (SIAT8-B) (Sialyltransferase X) (STX) (Sialytransferase St8Sia II) (ST8SiaII)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q92186
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q92186/entry
Mouse Swissprot No.
O35696
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O35696
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q07977
免疫原
Synthesized peptide derived from part region of human protein
特异性
SIA8B Polyclonal Antibody detects endogenous levels of protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a type II membrane protein that is thought to catalyze the transfer of sialic acid from CMP-sialic acid to N-linked oligosaccharides and glycoproteins. The encoded protein may be found in the Golgi apparatus and may be involved in the production of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). This protein is a member of glycosyltransferase family 29. [provided by RefSeq, Jul 2008],
组织表达
Highly expressed in fetal brain, kidney and heart and to a much lesser extent in adult heart and thymus.
细胞定位
Golgi apparatus membrane ; Single-pass type II membrane protein .
功能
function:May transfer sialic acid through alpha-2,8-linkages to the alpha-2,3-linked and alpha-2,6-linked sialic acid of N-linked oligosaccharides of glycoproteins and may be involved in PSA (polysialic acid) expression.,online information:GlycoGene database,online information:ST8Sia II,pathway:Protein modification; protein glycosylation.,similarity:Belongs to the glycosyltransferase 29 family.,tissue specificity:Highly expressed in fetal brain, kidney and heart and to a much lesser extent in adult heart and thymus.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
