产品名称
CEGT Rabbit Polyclonal Antibody
蛋白名称
Ceramide glucosyltransferase (EC 2.4.1.80) (GLCT-1) (Glucosylceramide synthase) (GCS) (UDP-glucose ceramide glucosyltransferase) (UDP-glucose:N-acylsphingosine D-glucosyltransferase)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q16739
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q16739/entry
Mouse Swissprot No.
O88693
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O88693
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q9R0E0
免疫原
Synthesized peptide derived from part region of human protein
特异性
CEGT Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes an enzyme that catalyzes the first glycosylation step in the biosynthesis of glycosphingolipids, which are membrane components containing lipid and sugar moieties. The product of this reaction is glucosylceramide, which is the core structure of many glycosphingolipids. [provided by RefSeq, Dec 2014],
组织表达
Found in all tissues examined.
细胞定位
Golgi apparatus membrane ; Multi-pass membrane protein .
信号通路
Sphingolipid metabolism;
功能
catalytic activity:UDP-glucose + N-acylsphingosine = UDP + D-glucosyl-N-acylsphingosine.,function:Catalyzes the first glycosylation step in glycosphingolipid biosynthesis, the transfer of glucose to ceramide. May also serve as a "flippase".,online information:GlycoGene database,pathway:Lipid metabolism; sphingolipid metabolism.,similarity:Belongs to the glycosyltransferase 2 family.,tissue specificity:Found in all tissues examined.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
