产品名称
TFF2 Rabbit Polyclonal Antibody
蛋白名称
Trefoil factor 2 (Spasmolysin) (Spasmolytic polypeptide) (SP)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q03403
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q03403/entry
Mouse Swissprot No.
Q03404
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q03404
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q09030
免疫原
Synthesized peptide derived from part region of human protein
特异性
TFF2 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. The encoded protein inhibits gastric acid secretion. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008],
功能
function:Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains.,similarity:Contains 2 P-type (trefoil) domains.,tissue specificity:Stomach.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
