BD-PN2865

OCLN Rabbit Polyclonal Antibody

常规抗体

OCLN

Occludin;OCN

WB

Human,Mouse,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.

100506658

Q16625

https://www.uniprot.org/uniprotkb/Q16625/entry

Q61146

http://www.uniprot.org/uniprot/Q61146

Q6P6T5

http://www.uniprot.org/uniprot/O54941Q6P6T5

Synthesized peptide derived from part region of human protein. AA350-400

OCLN Polyclonal Antibody detects endogenous levels of protein.

WB 1:500-2000 IF 1:100-300 ELISA 1:5000-20000 Not yet tested in other applications.

57kD

-20°C/1 year

Polyclonal, Rabbit,IgG

This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011],

Localized at tight junctions of both epithelial and endothelial cells. Highly expressed in kidney. Not detected in testis.

Cell membrane ; Multi-pass membrane protein . Cell junction, tight junction .

Cell adhesion molecules (CAMs);Tight junction;Leukocyte transendothelial migration;Pathogenic Escherichia coli infection;

protein complex assembly,?cellular amino acid derivative metabolic process,?sulfur metabolic process,?nucleoside metabolic process,?ribonucleoside metabolic process,?purine nucleoside metabolic process,?macromolecular complex subunit organization,?purine ribonucleoside metabolic process,?S-adenosylhomocysteine metabolic process,?S-adenosylmethionine metabolic process,?macromolecular complex assembly,?protein complex biogenesis,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.