产品名称
DEST Rabbit Polyclonal Antibody
蛋白名称
Destrin (Actin-depolymerizing factor) (ADF)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P60981
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P60981/entry
Mouse Swissprot No.
Q9R0P5
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9R0P5
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q7M0E3
免疫原
Synthesized peptide derived from part region of human protein
特异性
DEST Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The product of this gene belongs to the actin-binding proteins ADF family. This family of proteins is responsible for enhancing the turnover rate of actin in vivo. This gene encodes the actin depolymerizing protein that severs actin filaments (F-actin) and binds to actin monomers (G-actin). Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],
组织表达
Widely distributed in various tissues.
细胞定位
actin cytoskeleton,cortical actin cytoskeleton,extracellular exosome,
功能
function:Actin-depolymerizing protein. Severs actin filaments (F-actin) and binds to actin monomers (G-actin). Acts in a pH-independent manner.,similarity:Belongs to the actin-binding proteins ADF family.,similarity:Contains 1 ADF-H domain.,tissue specificity:Widely distributed in various tissues.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
