产品名称
DNJC2 Rabbit Polyclonal Antibody
基因名称
DNAJC2 MPHOSPH11 MPP11 ZRF1
蛋白名称
DnaJ homolog subfamily C member 2 (M-phase phosphoprotein 11) (Zuotin-related factor 1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q99543
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q99543/entry
Mouse Swissprot No.
P54103
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P54103
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q7TQ20
免疫原
Synthesized peptide derived from part region of human protein AA range: 406-456
特异性
DNJC2 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Cytoplasm, cytosol .
功能
PTM:Phosphorylated in M (mitotic) phase.,similarity:Contains 1 J domain.,similarity:Contains 2 SANT domains.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
