产品名称
DC1L1 Rabbit Polyclonal Antibody
蛋白名称
Cytoplasmic dynein 1 light intermediate chain 1 (LIC1) (Dynein light chain A) (DLC-A) (Dynein light intermediate chain 1, cytosolic)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9Y6G9
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Y6G9/entry
Mouse Swissprot No.
Q8R1Q8
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8R1Q8
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q9QXU8
免疫原
Synthesized peptide derived from part region of human protein AA range: 292-342
特异性
DC1L1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene belongs to light intermediate subunit family, whose members are components of the multiprotein cytoplasmic dynein complex, which is involved in intracellular trafficking and chromosome segregation during mitosis. The protein plays a role in moving the spindle assembly checkpoint (SAC) from kinetochores to spindle poles. The protein may also mediate binding to other cargo molecules to facilitate intracellular vesicle trafficking. [provided by RefSeq, Jul 2016],
组织表达
Cerebellum,Coronary artery,Epithelium,Human testis,
细胞定位
Cytoplasm . Chromosome, centromere, kinetochore . Cytoplasm, cytoskeleton, spindle pole .
功能
function:May play a role in binding dynein to membranous organelles or chromosomes. May associate with the heavy chains in the dynein head where they might regulate enzyme activity.,PTM:Phosphorylated.,similarity:Belongs to the dynein light intermediate chain family.,subunit:Consists of at least 3 heavy chains (alpha, beta and gamma), 2 intermediate chains and 8 light chains.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
