产品名称
MATR3 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P43243
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P43243/entry
Mouse Swissprot No.
Q8K310
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8K310
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P43244
免疫原
Synthesized peptide derived from part region of human protein AA range: 181-231
特异性
MATR3 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
matrin 3(MATR3) Homo sapiens This gene encodes a nuclear matrix protein, which is proposed to stabilize certain messenger RNA species. Mutations of this gene are associated with distal myopathy 2, which often includes vocal cord and pharyngeal weakness. Alternatively spliced transcript variants, including read-through transcripts composed of the upstream small nucleolar RNA host gene 4 (non-protein coding) and matrin 3 gene sequence, have been identified. Pseudogenes of this gene are located on chromosomes 1 and X. [provided by RefSeq, Aug 2013],
组织表达
Amygdala,Brain,Epithelium,Fetal kidney,Hypothalamus,Liver,Retina,Skin,
功能
function:May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer may play a role in nuclear retention of defective RNAs.,similarity:Contains 1 matrin-type zinc finger.,similarity:Contains 2 RRM (RNA recognition motif) domains.,subunit:Part of complex consisting of SFPQ, NONO and MATR3.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
