产品名称
CASS4 Rabbit Polyclonal Antibody
蛋白名称
Cas scaffolding protein family member 4 (HEF-like protein) (HEF1-EFS-p130Cas-like protein) (HEPL)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9NQ75
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NQ75/entry
Mouse Swissprot No.
Q08EC4
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q08EC4
免疫原
Synthesized peptide derived from part region of human protein AA range: 302-352
特异性
CASS4 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
alternative products:Experimental confirmation may be lacking for some isoforms,function:Possible docking protein which may play a role for tyrosine-kinase-based signaling related to cell adhesion. Regulates FAK activity, focal adhesion integrity, and cell spreading.,PTM:Phosphorylated on tyrosines by SRC.,similarity:Belongs to the CAS family.,similarity:Contains 1 SH3 domain.,subunit:Interacts (via SH3 domain) with focal adhesion kinase (via C-terminus).,tissue specificity:Expressed abundantly in lung and spleen. Also highly expressed in ovarian and leukemia cell lines.,
组织表达
Expressed abundantly in lung and spleen. Also highly expressed in ovarian and leukemia cell lines.
细胞定位
Cytoplasm, cytoskeleton . Cell junction, focal adhesion .
功能
alternative products:Experimental confirmation may be lacking for some isoforms,function:Possible docking protein which may play a role for tyrosine-kinase-based signaling related to cell adhesion. Regulates FAK activity, focal adhesion integrity, and cell spreading.,PTM:Phosphorylated on tyrosines by SRC.,similarity:Belongs to the CAS family.,similarity:Contains 1 SH3 domain.,subunit:Interacts (via SH3 domain) with focal adhesion kinase (via C-terminus).,tissue specificity:Expressed abundantly in lung and spleen. Also highly expressed in ovarian and leukemia cell lines.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
