产品名称
TKT Rabbit Polyclonal Antibody
蛋白名称
Transketolase (TK) (EC 2.2.1.1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P29401
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P29401/entry
Mouse Swissprot No.
P40142
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P40142
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P50137
免疫原
Synthesized peptide derived from part region of human protein AA range: 125-175
特异性
TKT Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a thiamine-dependent enzyme which plays a role in the channeling of excess sugar phosphates to glycolysis in the pentose phosphate pathway. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2012],
组织表达
Brain,Epithelium,Human uterus,Kidney,Liver,Lymph,Platelet,Thymus,
细胞定位
nucleus,nucleoplasm,peroxisome,cytosol,vesicle,myelin sheath,extracellular exosome,
信号通路
Pentose phosphate pathway;
功能
catalytic activity:Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-ribose 5-phosphate + D-xylulose 5-phosphate.,cofactor:Binds 1 calcium ion per subunit.,cofactor:Binds 1 thiamine pyrophosphate per subunit.,disease:Has been implicated in the latent genetic disease Wernicke-Korsakoff syndrome (WKS) [MIM:277730]. WKS causes specific brain damage.,online information:Transketolase entry,similarity:Belongs to the transketolase family.,subunit:Homodimer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
