产品名称
NPY6R Rabbit Polyclonal Antibody
蛋白名称
Putative neuropeptide Y receptor type 6 (NPY6-R) (NPY Y1-like receptor) (Putative pancreatic polypeptide receptor 2) (PP2)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q99463
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q99463/entry
Mouse Swissprot No.
Q61212
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q61212
免疫原
Synthesized peptide derived from human protein . at AA range: 190-270
特异性
NPY6R Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
caution:Could be the product of a pseudogene. According to PubMed:97066888, PubMed:97066971 and PubMed:9013614, the human NPY6R gene is an expressed pseudogene containing a premature stop codon and encoding a non-functional truncated protein missing the last transmembrane domain. A single base pair deletion relative to the mouse ortholog, results in a truncated protein lacking the seventh transmembrane domain.,function:When expressed, is unable to bind pancreatic polypeptide (PP), neuropeptide Y (NPY), or peptide YY (PYY), suggesting that either it is functionally inactive or that it may have acquired a pancreatic polypeptide-independent function.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in heart, skeletal muscle, gastrointestinal tissues, spleen, brain and adrenal glands.,
组织表达
Expressed in heart, skeletal muscle, gastrointestinal tissues, spleen, brain and adrenal glands.
细胞定位
Membrane ; Multi-pass membrane protein .
功能
caution:Could be the product of a pseudogene. According to PubMed:97066888, PubMed:97066971 and PubMed:9013614, the human NPY6R gene is an expressed pseudogene containing a premature stop codon and encoding a non-functional truncated protein missing the last transmembrane domain. A single base pair deletion relative to the mouse ortholog, results in a truncated protein lacking the seventh transmembrane domain.,function:When expressed, is unable to bind pancreatic polypeptide (PP), neuropeptide Y (NPY), or peptide YY (PYY), suggesting that either it is functionally inactive or that it may have acquired a pancreatic polypeptide-independent function.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in heart, skeletal muscle, gastrointestinal tissues, spleen, brain and adrenal glands.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
