产品名称
TAAR8 Rabbit Polyclonal Antibody
基因名称
TAAR8 GPR102 TA5 TAR5 TRAR5
蛋白名称
Trace amine-associated receptor 8 (TaR-8) (Trace amine receptor 8) (G-protein coupled receptor 102) (Trace amine receptor 5) (TaR-5)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q969N4
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q969N4/entry
免疫原
Synthesized peptide derived from human protein . at AA range: 110-190
特异性
TAAR8 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is part of the trace amine receptor cluster on chromosome 6 and encodes an orphan G-protein coupled receptor. Upregulated expression of this gene in astroglial cells upon exposure to lipopolysaccharides suggests a function for the encoded protein in the brain. [provided by RefSeq, Jul 2016],
组织表达
Expressed in kidney and amygdala. Not expressed in other tissues or brain regions tested.
细胞定位
Cell membrane; Multi-pass membrane protein.
信号通路
Neuroactive ligand-receptor interaction;
功能
function:Orphan receptor. Could be a receptor for trace amines. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in kidney and amygdala. Not expressed in other tissues or brain regions tested.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
