产品名称
LT4R2 Rabbit Polyclonal Antibody
蛋白名称
Leukotriene B4 receptor 2 (LTB4-R 2) (LTB4-R2) (LTB4 receptor JULF2) (Leukotriene B4 receptor BLT2) (Seven transmembrane receptor BLTR2)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9NPC1
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NPC1/entry
Mouse Swissprot No.
Q9JJL9
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9JJL9
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q924U0
免疫原
Synthesized peptide derived from human protein . at AA range: 290-370
特异性
LT4R2 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
caution:It is uncertain whether Met-1 or Met-32 is the initiator.,function:Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Widely expressed.,
细胞定位
Cell membrane; Multi-pass membrane protein.
信号通路
Calcium;Neuroactive ligand-receptor interaction;
功能
caution:It is uncertain whether Met-1 or Met-32 is the initiator.,function:Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Widely expressed.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
