产品名称
TF2H3 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/2967
Human Swissprot No.
Q13889
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q13889/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/209357
Mouse Swissprot No.
Q8VD76
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8VD76
Rat Gene Link
https://www.uniprot.org/uniprot/288651
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q561R7
免疫原
Synthesized peptide derived from human TF2H3 AA range: 39-89
特异性
This antibody detects endogenous levels of TF2H3 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the TFB4 family. The encoded protein is a subunit of the core-TFIIH basal transcription factor and localizes to the nucleus. The encoded protein is involved in RNA transcription by RNA polymerase II and nucleotide excision repair and associates with the Cdk-activating kinase complex. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 14. [provided by RefSeq, Dec 2012],
功能
function:Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Anchors XPB.,similarity:Belongs to the TFB4 family.,subunit:One of the six subunits forming the core-TFIIH basal transcription factor.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
