产品名称
LT4R1 Rabbit Polyclonal Antibody
基因名称
LTB4R BLT BLT1 BLTR CMKRL1 GPR16 P2RY7
蛋白名称
Leukotriene B4 receptor 1 (LTB4-R 1) (LTB4-R1) (Chemoattractant receptor-like 1) (G-protein coupled receptor 16) (P2Y purinoceptor 7) (P2Y7)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q15722
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q15722/entry
Mouse Swissprot No.
O88855
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O88855
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q9R0Q2
免疫原
Synthesized peptide derived from part region of human protein
特异性
LT4R1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.,PTM:Phosphorylated by GRK6 upon leukotriene B4 binding; which promotes desensitization.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed at highest levels in heart, skeletal muscle and at lower levels in brain and liver. High level of expression in lymphoid tissues.,
组织表达
Expressed at highest levels in heart, skeletal muscle and at lower levels in brain and liver. High level of expression in lymphoid tissues.
细胞定位
Cell membrane; Multi-pass membrane protein.
信号通路
Neuroactive ligand-receptor interaction;
功能
function:Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.,PTM:Phosphorylated by GRK6 upon leukotriene B4 binding; which promotes desensitization.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed at highest levels in heart, skeletal muscle and at lower levels in brain and liver. High level of expression in lymphoid tissues.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
