产品名称
GP125 Rabbit Polyclonal Antibody
基因名称
GPR125 UNQ556/PRO1113
蛋白名称
Probable G-protein coupled receptor 125
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q8IWK6
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8IWK6/entry
Mouse Swissprot No.
Q7TT36
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q7TT36
免疫原
Synthesized peptide derived from part region of human protein
特异性
GP125 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the G protein-coupled receptor superfamily. This membrane protein may play a role in tumor angiogenesis through its interaction with the human homolog of the Drosophila disc large tumor suppressor gene. This gene is mapped to a candidate region of chromosome 4 which may be associated with bipolar disorder and schizophrenia. [provided by RefSeq, Oct 2012],
组织表达
Epithelium,Eye,Liver,
细胞定位
Membrane ; Multi-pass membrane protein .
功能
domain:Binds to DLG1 through its PDZ-binding motif.,function:Orphan receptor.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,similarity:Contains 1 Ig-like (immunoglobulin-like) domain.,similarity:Contains 5 LRR (leucine-rich) repeats.,subunit:Interacts with DLG1.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
