产品名称
GP182 Rabbit Polyclonal Antibody
蛋白名称
G-protein coupled receptor 182
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
O15218
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O15218/entry
Mouse Swissprot No.
P43142
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P43142
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P31392
免疫原
Synthesized peptide derived from human protein . at AA range: 190-270
特异性
GP182 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
Adrenomedullin is a potent vasodilator peptide that exerts major effects on cardiovascular function. This gene encodes a seven-transmembrane protein that belongs to the family 1 of G-protein coupled receptors. Studies of the rat counterpart suggest that the encoded protein may function as a receptor for adrenomedullin. [provided by RefSeq, Jul 2008],
组织表达
Highly expressed in heart, skeletal muscle, immune system, adrenal gland and liver.
细胞定位
Cell membrane; Multi-pass membrane protein.
功能
caution:Was originally (PubMed:9367907) thought to be a receptor for adrenomedullin.,function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Highly expressed in heart, skeletal muscle, immune system, adrenal gland and liver.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.