Cn|En

现货抗体产品库

HEM1 Rabbit Polyclonal Antibody

产品详情 相关文献 产品问答 相关产品

产品基本信息

产品货号
BD-PN3569
产品名称
HEM1 Rabbit Polyclonal Antibody
类别
常规抗体
基因名称
ALAS1 ALAS3 ALASH OK/SW-cl.121
蛋白名称
HEM1
推荐应用
WB
反应种属
Human,Mouse,Rat
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
211
Human Gene Link
https://www.uniprot.org/uniprot/211
Human Swissprot No.
P13196
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P13196/entry
Mouse Gene ID
11655
Mouse Gene Link
https://www.uniprot.org/uniprot/11655
Mouse Swissprot No.
Q8VC19
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8VC19
Rat Gene ID
65155
Rat Gene Link
https://www.uniprot.org/uniprot/65155
Rat Swissprot No.
P13195
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P13195
免疫原
Synthesized peptide derived from human HEM1 AA range: 87-137
特异性
This antibody detects endogenous levels of HEM1 at Human/Mouse/Rat
稀释度
WB 1:500-2000
参考分子量
70kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015],
细胞定位
Mitochondrion inner membrane ; Peripheral membrane protein . Localizes to the matrix side of the mitochondrion inner membrane. .
功能
catalytic activity:Succinyl-CoA + glycine = 5-aminolevulinate + CoA + CO(2).,cofactor:Pyridoxal phosphate.,miscellaneous:There are two delta-ALA synthetase in vertebrates: an erythroid- specific form and one (housekeeping) which is expressed in all tissues.,pathway:Porphyrin metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from glycine: step 1/1.,similarity:Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.,subunit:Homodimer.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

相关文献

产品问答

相关产品

免责声明| 法律支持| 联系方式

市场:027-65023363   行政/人事:027-62439686   邮箱:marketing@brainvta.com  

销售总监:张经理  18995532642  华东区:陈经理 18013970337   华南区:王经理 13100653525   华中/西区:杨经理 18186518905   华北区:张经理 18893721749

地址:中国武汉东湖高新区光谷七路128号中科开物产业园1号楼

Copyright © 武汉枢密脑科学技术有限公司. All RIGHTS RESERVED.
鄂ICP备2021009124号 DIGITAL BY VTHINK