产品名称
GPR61 Rabbit Polyclonal Antibody
蛋白名称
Probable G-protein coupled receptor 61 (Biogenic amine receptor-like G-protein coupled receptor)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9BZJ8
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9BZJ8/entry
Mouse Swissprot No.
Q8C010
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8C010
免疫原
Synthesized peptide derived from human protein . at AA range: 190-270
特异性
GPR61 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene belongs to the G-protein coupled receptor 1 family. G protein-coupled receptors contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. The protein encoded by this gene is most closely related to biogenic amine receptors. [provided by RefSeq, Jul 2008],
组织表达
Expressed in brain; detected in frontal and temporal lobes, occipital pole, amygdala and hippocampus (PubMed:11690637, PubMed:29226084). Also expressed in testis (PubMed:11690637, PubMed:29226084) and T cells, B cells, and monocyte (PubMed:29226084). Low expression in many other tissues (PubMed:11690637, PubMed:29226084). Widely expressed in the hippocampus (at protein level).
细胞定位
Cell membrane ; Multi-pass membrane protein . Endosome membrane ; Multi-pass membrane protein . Colocalizes with ARRB2/beta-arrestin-2 in the endosome (PubMed:28827538). .
功能
function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in brain; detected in frontal and temporal lobes, occipital pole, amygdala and hippocampus. Also expressed in testis. Low expression in many other tissues.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
