BD-PN3572

IKZF5 Rabbit Polyclonal Antibody

常规抗体

IKZF5 ZNFN1A5

IKZF5

WB

Human,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

64376

https://www.uniprot.org/uniprot/64376

Q9H5V7

https://www.uniprot.org/uniprotkb/Q9H5V7/entry

67143

https://www.uniprot.org/uniprot/67143

Q8BU00

https://www.uniprot.org/uniprotkb/Q8BU00

Synthesized peptide derived from human IKZF5 AA range: 210-260

This antibody detects endogenous levels of IKZF5 at Human/Mouse

WB 1：500-2000

46kD

-20°C/1 year

Polyclonal, Rabbit,IgG

Members of the Ikaros (ZNFN1A1; MIM 603023) family of transcription factors, which includes Pegasus, are expressed in lymphocytes and are implicated in the control of lymphoid development.[supplied by OMIM, Jul 2002],

Expressed in brain, heart, skeletal muscle, kidney, and liver. Expressed in the hematopoietic cell lines MOLT-4, NALM-6 and K-562. Highly expressed in THP-1 and M-07e cell lines, which have characteristics of myeloid and early megakaryocytic cells respectively.

Nucleus .

domain:C-terminal zinc fingers mediate homodimerization.,domain:The N-terminal zinc fingers are involved in sequence-specific DNA binding and heterotypic associations with other family members.,function:DNA-binding protein that binds to the 5'GNNTGTNG-3' core sequence. Transcriptional repressor.,miscellaneous:'Pegasus' was the winged horse in Greek mythology.,similarity:Belongs to the Ikaros C2H2-type zinc-finger protein family.,similarity:Contains 5 C2H2-type zinc fingers.,subunit:Self-associates and interacts with other family members; IKZF1, IKZF2, IKZF3 AND IKZF4.,tissue specificity:Expressed in brain, heart, skeletal muscle, kidney, and liver. Expressed in the hematopoietic cell lines MOLT-4, NALM-6 and K562. Highly expressed in THP-1 and Mo7e-IL3 cell lines, which have characteristics of myeloid and early megakaryocytic cells respectively.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.