产品名称
CALRL Rabbit Polyclonal Antibody
蛋白名称
Calcitonin gene-related peptide type 1 receptor (CGRP type 1 receptor) (Calcitonin receptor-like receptor)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q16602
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q16602/entry
Mouse Swissprot No.
Q9R1W5
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9R1W5
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q63118
免疫原
Synthesized peptide derived from human protein . at AA range: 40-120
特异性
CALRL Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3 (By similarity). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.,similarity:Belongs to the G-protein coupled receptor 2 family.,subunit:Heterodimer of CALCRL and RAMP1, RAMP2 or RAMP3.,tissue specificity:Predominantly expressed in the lung and heart.,
组织表达
Predominantly expressed in the lung and heart.
细胞定位
Cell membrane ; Multi-pass membrane protein.
信号通路
Neuroactive ligand-receptor interaction;Vascular smooth muscle contraction;
功能
function:Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3 (By similarity). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.,similarity:Belongs to the G-protein coupled receptor 2 family.,subunit:Heterodimer of CALCRL and RAMP1, RAMP2 or RAMP3.,tissue specificity:Predominantly expressed in the lung and heart.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
