产品名称
BKRB2 Rabbit Polyclonal Antibody
蛋白名称
B2 bradykinin receptor (B2R) (BK-2 receptor)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P30411
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P30411/entry
Mouse Swissprot No.
P32299
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P32299
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P25023
免疫原
Synthesized peptide derived from human protein . at AA range: 140-220
特异性
BKRB2 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Alternate start codons result in two isoforms of the protein. [provided by RefSeq, Jul 2008],
组织表达
Ubiquitous. Widespread in normal smooth muscle tissue and neurons.
细胞定位
Cell membrane; Multi-pass membrane protein.
信号通路
Calcium;Neuroactive ligand-receptor interaction;Complement and coagulation cascades;Regulates Actin and Cytoskeleton;
功能
function:Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.,online information:Bradykinin receptor entry,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Ubiquitous. Widespread in normal smooth muscle tissue and neurons.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.