产品名称
NPB Rabbit Polyclonal Antibody
蛋白名称
Neuropeptide B (Preproprotein L7) (hPPL7) [Cleaved into: Neuropeptide B-23 (NPB23) (hL7); Neuropeptide B-29 (NPB29) (hL7C)]
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q8NG41
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8NG41/entry
Mouse Swissprot No.
Q8K4P1
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8K4P1
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q8K4P2
免疫原
Synthesized peptide derived from human protein . at AA range: 1-50
特异性
NPB Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the neuropeptide B/W family of proteins and preproprotein that is proteolytically processed to generate multiple protein products. The encoded products include neuropeptide B-23 and a C-terminally extended form, neuropeptide B-29, which are characterized by an N-terminal brominated tryptophan amino acid. Both of the encoded peptides bind with higher affinity to neuropeptide B/W (NPB/W) receptor 1 compared to the related NPB/W receptor 2. These peptides may regulate feeding, pain perception, and stress in rodents. [provided by RefSeq, Jul 2015],
组织表达
Widely expressed in the central nervous system. High levels are found in substantia nigra, hypothalamus, hippocampus, spinal cord, placenta and fetal brain; lower levels are found in testis, uterus and ovary. Also detected at high levels in colorectal adenocarcinoma.
功能
function:May be involved in the regulation of feeding, neuroendocrine system, memory, learning and in the afferent pain pathway.,similarity:Belongs to the neuropeptide B/W family.,tissue specificity:Widely expressed in the central nervous system. High levels are found in substantia nigra, hypothalamus, hyppocampus, spinal cord, placenta and fetal brain; lower levels are found in testis, uterus and ovary. Also detected at high levels in colorectal adenocarcinoma.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
