产品名称
FGGY Rabbit Polyclonal Antibody
蛋白名称
FGGY carbohydrate kinase domain-containing protein (EC 2.7.1.-)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q96C11
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q96C11/entry
Mouse Swissprot No.
A2AJL3
Mouse Swissprot Link
http://www.uniprot.org/uniprot/A2AJL3
免疫原
Synthesized peptide derived from human protein . at AA range: 491-540
特异性
FGGY Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein that phosphorylates carbohydrates such as ribulose, ribitol, and L-arabinitol. Genome-wide association studies in some populations have found an association between polymorphisms in this gene and sporadic amyotrophic lateral sclerosis, but studies of other populations have not been able to replicate this association. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013],
组织表达
Expressed in kidney, lung and small intestine and to a lower extent in liver and detected in cerebrospinal fluid (at protein level).
功能
developmental stage:Expressed in fetal brain (at protein level).,disease:Defects in FGGY are associated with sporadic amyotrophic lateral sclerosis (ALS) [MIM:105400]. Amyotrophic lateral sclerosis is a neurodegenerative disorder affecting upper and lower motor neurons and resulting in fatal paralysis. Sensory abnormalities are absent. Death usually occurs within 2 to 5 years. The etiology of amyotrophic lateral sclerosis is likely to be multifactorial, involving both genetic and environmental factors.,similarity:Belongs to the FGGY kinase family.,tissue specificity:Expressed in kidney, lung and small intestine and to a lower extent in liver and detected in cerebrospinal fluid (at protein level).,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
