产品名称
PGRP3 Rabbit Polyclonal Antibody
蛋白名称
Peptidoglycan recognition protein 3 (Peptidoglycan recognition protein I-alpha) (PGLYRPIalpha) (PGRP-I-alpha) (Peptidoglycan recognition protein intermediate alpha)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q96LB9
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q96LB9/entry
Mouse Swissprot No.
A1A547
Mouse Swissprot Link
http://www.uniprot.org/uniprot/A1A547
免疫原
Synthesized peptide derived from human protein . at AA range: 51-100
特异性
PGRP3 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. These proteins are part of the innate immune system and recognize peptidoglycan, a ubiquitous component of bacterial cell walls. This antimicrobial protein binds to murein peptidoglycans of Gram-positive bacteria. [provided by RefSeq, Oct 2014],
组织表达
Detected in skin epidermis, eccrine sweat glands and ducts, ciliary body epithelial cells of the eye, in small intestine, colon, stomach and in mature epithelial cells of the tongue (at protein level). Highly expressed in skin and esophagus, expressed also in tonsils and thymus and to a much lesser extent in the stomach, descending colon, rectum and brain.
功能
function:Binds to murein peptidoglycans (PGN) of Gram-positive bacteria. May play a role in innate immunity.,similarity:Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.,subunit:Monomer and dimer.,tissue specificity:Highly expressed in the esophagus, expressed also in tonsils and thymus and to a much lesser extent in the stomach, descending colon, rectum and brain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
